What Is Glycine? Benefits for Skin and Scientific Information
What Is Glycine?
Glycine is one of the smallest and simplest amino acids. It is naturally synthesized in the body and is among the basic building blocks of the collagen protein. In cosmetics, it is used due to its moisturizing, anti-aging, and skin barrier–supporting properties.
Glycine is found in skincare products both on its own and in combination with other amino acids. It is widely used in serums, moisturizers, anti-aging creams, and restorative masks.
Key Scientific Information
Chemical Structure: H2N-CH2-COOH
Physical Properties: Water-soluble; has a colorless crystalline structure.
Mechanism of Action: Contributes to collagen synthesis, supports cell renewal, and increases moisture-retention capacity.
Natural Sources: Meat, fish, dairy products, legumes, and gelatin.
Benefits for Skin
Supports Collagen Synthesis
Glycine is a key amino acid that makes up about one-third of collagen. By supporting collagen production, it improves skin firmness and helps reduce signs of aging.
Moisturizing Effect
Thanks to its hygroscopic nature, it helps retain water in the skin. This helps maintain the skin’s moisture balance and forms a barrier against dryness.
Anti-Aging Properties
By improving skin elasticity, it helps reduce the appearance of fine lines and wrinkles.
Soothing Effect
By reducing redness in irritated and sensitive skin, it helps the skin look calmer.
Strengthens the Skin Barrier
By supporting lipid and protein synthesis, it helps repair the skin barrier and provides protection against environmental factors.
Scientific References
- Hou, T. et al. (2019). Role of glycine in collagen structure and function. International Journal of Biological Macromolecules, 128, 1–8.
https://pubmed.ncbi.nlm.nih.gov/30059860/
- Barbul, A. (2008). Nutrition and wound healing: the role of glycine. Advances in Wound Care, 1(4), 159–165.
https://pubmed.ncbi.nlm.nih.gov/28715720/
- Proksch, E. et al. (2008). Amino acids and skin barrier function. International Journal of Cosmetic Science, 30(3), 131–138.
https://pubmed.ncbi.nlm.nih.gov/19043850/